PIPELINE

Pipeline

OBPharm is advancing a biomarker-driven pipeline of peptide and monoclonal antibody therapeutics for obesity and obesity-associated cardiovascular–kidney–metabolic (CKM) disease. Our model is intentionally translation-first: we start from mechanism-linked signals, design for developability, and progress partner-ready programs with an IND-oriented path in mind.

Development framework

We apply a stage-gated process that connects mechanistic discovery to clinical endpoints. The output isn’t just “a target”—it’s a coherent package: what to build, how to test it, and which biomarkers prove the story.

Discovery
Biomarker-linked target selection
Design
Modality choice + developability constraints
Validation
Functional readouts aligned to translation
Path
IND-oriented execution plan
What makes it different

Across peptide and mAb programs, we combine proprietary enabling technologies with rigorous biomarker strategy. We share full datasets, protocols, and timelines under CDA for qualified partners.

Biomarker-first program definition
Modality-specific engineering
Scale-up and IND readiness
Request pipeline summary (CDA)

Partnering inquiries welcome.

PROGRAMS

Two lead programs in development

OB001 is a peptide program derived from adiponectin biology. OB002 is a monoclonal antibody program aimed at a biomarker-linked inflammatory axis in obesity-associated cardiovascular disease.

Partnering

We are open to licensing and strategic collaborations across preclinical development and clinical-stage execution.